By M. Ola
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Characterization of the signaling interactions that promote the survival and growth of developing retinal ganglion cells in culture. Neuron. 1995 Oct;15(4):805-19.  Min D, Xiao-Bo X, Si-Qi X. BDNF regulates GLAST and glutamine synthetase in mouse retinal Müller cells. J Cell Physiol. 2011 Mar 29. 22762. [Epub ahead of print]  Misra GP, Singh RS, Aleman TS, Jacobson SG, Gardner TW, Lowe TL. Subconjunctivally implantable hydrogels with degradable and thermoresponsive properties for sustained release of insulin to the retina.
Wong CG, Rich KA, Liaw LH, Hsu HT, Berns MW. Intravitreal VEGF and bFGF produce florid retinal neovascularization and hemorrhage in the rabbit. Curr Eye Res 2001; 22: 140-7. Yamagishi S, Amano S, Inagaki Y, Okamoto T, Koga K, Sasaki N, Yamamoto H, Takeuchi M, Makita Z. Advanced glycation end products-induced apoptosis and overexpression of vascular endothelial growth factor in bovine retinal pericytes. Biochem Biophys Res Commun. 2002 Jan 25;290(3):973-8. Yamagishi S, Matsui T, Nakamura K, Takeuchi M, Imaizumi T.
1998). 3. , 2006). In the process of glycation, AGE peptides that are released as degradation products, which partly occur through proteolysis of the matrix component are commonly named as glycotoxins. , 2000). Toxicity of glycated polypeptides may be due to the AGE modification or due to the aggregation state of the polypeptides. Glycotoxins are very reactive on entering blood circulation. Non elimination of these proteins through the kidneys leads to recirculating AGE peptides which can generate new AGE products that react with other plasma or tissue components.